KING EDWARD MEMORIAL HOSPITAL

Background History

In 1959, Diabetes clinic was started by Dr. J C  Patel and Dr. M K Dhirwani (Hon. Asstt. Physician). In 1962, Endocrinology Clinic was started by Prof P. Raghavan and Dr. S D Bhandarkar (Hon. Asstt. Physician).  Dr. S D Bhandarkar also started looking after the Thyroid clinic which was initiated by Dr. Satoskar.  In 1971, 12 indoor beds were allotted for diabetes and endocrinology services.

In 1973, Dr. Bhandarkar was given charge of both the Endocrinology and Diabetes clinics after the untimely demise of Dr. Dhirwani. In 1979, the Diabetes and Endocrinology clinics were combined into one “Division of Endocrinology and Metabolic Disorders”.  In 1979, “Puberty and Growth Clinic” was added to the activities of the Department.  In 1980, the Division was given 12 more beds, making a total to 24 beds.  In 1981, the Division was recognized provisionally by the National Board of Examinations to enroll post-graduate students for MNAMS (Endocrinology). In 1983, the division was recognized by the University of Bombay to enroll students for DM (Endocrinology).  The Division of Endocrinology and Metabolic Disorders was re-designated as the Department of Endocrinology.  In 1989 radioimmuno hormone assay laboratory was started with the financial support of the Bai Vijkorbai Mayaram Khakhar Foundtion Trust.

In 1991, Dr. Padma S Menon took over the department as Prof. and Head of Department. Under her guidance, not only patient care, also the post graduate training and clinical data capturing improved over time. She upgraded the lab machinery to automated chemiluminescent assays. Pituitary tumor management was streamlined, by regular meetings with neurosurgeons. Research (academic/drug) trial set up was established. In 2001 DXA scanner for bone mineral density measurement was installed.

In 2004, Dr. Nalini S Shah took over the department as Prof. and Head of Department. Pediatric Endocrinology services were added and we have pan India referrals for pediatric endocrine disorders. Our department is unique, where both pediatric and adult endocrinology is catered too. In 2007 DM (Endocrinology) course got MCI recognition.  In 2007 Molecular endocrinology laboratory was established for conducting research on genetic aspects of Endocrine disorders. For these research projects department has been awarded DBT/DST grants. She further upgraded the lab machinery by adding fully automated high output chemiluminescene machine, and HbA1c Analyzer.  Patient care and post graduate training was furthered with interdepartmental meeting (Adrenal, Pituitary, Thyroid, DSD, and H&N), inter-hospital endocrine meets (local/national). Our original research work publications (n= 140), have given internationally  recognition to the department. As the result of which department was chosen as the first international center by the US Endocrine Society, for Ambassador Exchange programmein 2013.

Staff

Faculty

Non Teaching Staff:

Research

Resident

Bonded Assistant Professor

Working Schedule of Department

Endocrine Oncology OPD Started from year 2019 in our Department.

Peripheral Clinics- New Services Instituted since 2011

• Peripheral linkage services clinics at Cooper Hospital, Bandra Bhabha Hospital and six peripheral dispensaries in MCGM once per week. (Total eight additional peripheral clinics per week through MCGM linkage services.

Hormone  Assay Workload  from Jan 2017 to Jan 2018

Hormone Assay Workload 2018

Hormone Assay Workload 2019

Hormone Assay Workload 2020

OPD Workload:

The average OPD attendance patients-visits per year are as follows

Indoor:

Department has 30 beds ( 15 for male and 15 for female ) on indoor basis.

Laboratory Facilities:

The department has an attached Hormone Assay Laboratory where following machine are available

Fully Automated Chemiluminescence Machines- 2

Fully Automated Biochemistry Autoanalyzer- 1

HbA1c analyzer by HPLC method- 1

Following tests are routinely performed in Hormone Assay Lab

• T3, T4, TSH
• FBS and PLBS
• HbA1c
• AMA
• LH
• FSH
• Prolactin
• Testosterone
• Cortisol
• PG Growth Hormone
• ACTH
• PTH
• IGF 1
• IGF BP3

Other Facilities:

• Molecular Endocrine Laboratory for research purpose to assess genotype phenotype correlation of various endocrine disorders
• Bone Mineral Densitometry ( DXA Scan)

Clinical Material & Infrastructure – Endocrinology

CME

Publication

Research

1. 68Ga-DOTATATE PET/CT of Ectopic Cushing Syndrome Due to Appendicular Carcinoid. Diwaker C, Shah RK, Patil V, Jadhav S, Lila A, Bandgar T, Shah N.Clin Nucl Med. 2019 Sep 12. doi: 10.1097/RLU.0000000000002766. [Epub ahead of print]
2. Tumor induced osteomalacia in head and neck region: single center experience and systematic review. Shah R, Lila AR, Jadhav S, Patil VA, Mahajan A, Sonawane S, Thadani P, Dcruz AK, Pai PS, Bal M, Kane S, Shah N, Bandgar TR. Endocr Connect. 2019 Sep 1. pii: EC-19-0341.R1. doi: 10.1530/EC-19-0341. [Epub ahead of print]
3. Radiological differentiation of phaeochromocytoma from other malignant adrenal masses: importance of wash-in characteristics on multiphase CECT. Goroshi M, Jadhav SS, Sarathi V, Lila AR, Patil VA, Shah R, Hira P, Sharma R, Goroshi S, Fernandes G, Rojekar A, Dalvi A, Bakshi G, Prakash G, Shah NS, Bandgar TR. Endocr Connect. 2019 Jul 1;8(7):898-905. doi: 10.1530/EC-19-0198.
4. Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes. Husain M, Birkenfeld AL, Donsmark M, Dungan K, Eliaschewitz FG, Franco DR, Jeppesen OK, Lingvay I, Mosenzon O, Pedersen SD, Tack CJ, Thomsen M, Vilsbøll T, Warren ML, Bain SC; PIONEER 6 Investigators.N Engl J Med. 2019 Aug 29;381(9):841-851. doi: 10.1056/NEJMoa1901118. Epub 2019 Jun 11.
5. Corrigendum to ‘A novel gross indel in the growth hormone releasing hormone receptor gene of Indian IGHD patients.’ [Growth Hormone & IGF Research 24 (2014) 227-232]. Kale S, Budyal S, Kasaliwal R, Shivane V, Raghavan V, Lila A, Bandgar T, Shah N.Growth Horm IGF Res. 2019 Apr 29. pii: S1096-6374(19)30021-8. doi: 10.1016/j.ghir.2019.04.001. [Epub ahead of print] No abstract available.
6. SYMPATHETIC PARAGANGLIOMA: A SINGLE-CENTER EXPERIENCE FROM WESTERN INDIA.Jaiswal SK, Sarathi V, Memon SS, Goroshi M, Jadhav S, Prakash G, Dalvi A, Lila AR, Bandgar T, Shah NS.Endocr Pract. 2019 Mar;25(3):211-219. doi: 10.4158/EP-2018-0480.
7. Primary pigmented nodular adrenocortical disease (PPNAD): single centre experience. Memon SS, Thakkar K, Patil V, Jadhav S, Lila AR, Fernandes G, Bandgar TR, Shah NS.J Pediatr Endocrinol Metab. 2019 Apr 24;32(4):391-397. doi: 10.1515/jpem-2018-0413.
8. Virilising ovarian tumors: a single center experience. Sehemby MAS, Bansal PAK, Sarathi V, Kolhe A, Kothari K, Jadhav S, Lila AR, Bandgar TR, Shah N. Endocr Connect. 2018 Nov 1. pii: EC-18-0360.R1. doi: 10.1530/EC-18-0360. [Epub ahead of print]
9. Coexistent Pituitary Adenoma with Rathke’s Cleft Cyst: A Case Series. Jagtap VS, Lila AR, Sarathi V, Bukan AP, Bandgar TR, Shah NS. J Assoc Physicians India. 2018 Mar;66(3):42-6.
10. First Trimester Thyroid Function Tests: Normative Data from Western India. Nambiar VM, Lila AR, Bandgar TR, Shah NS. Indian J Endocrinol Metab. 2018 Jul-Aug;22(4):574-575. doi: 10.4103/ijem.IJEM_178_18. No abstract available
11. Sellar Paraganglioma. Karlekar M, Kumar S, Jadhav S, Lila A, Bandgar T, Shah N. Clin Nucl Med. 2018 Aug;43(8):591-592. doi: 10.1097/RLU.0000000000002157.
12. Alveolar Soft Part Sarcoma Presenting as Hypervascular Adrenal Metastasis. Goroshi M, Lila AR, Bandgar T, Shah NS.World J Nucl Med. 2018 Jan-Mar;17(1):62-64. doi: 10.4103/wjnm.WJNM_8_17.PMID:
13. Genotype phenotype correlation in Asian Indian von Hippel-Lindau (VHL) syndrome patients with pheochromocytoma/paraganglioma. Lomte N, Kumar S, Sarathi V, Pandit R, Goroshi M, Jadhav S, Lila AR, Bandgar T, Shah NS. Fam Cancer. 2018 Jul;17(3):441-449. doi: 10.1007/s10689-017-0058-y.
14. Efficacy and safety of once-monthly pasireotide in Cushing’s disease: a 12 month clinical trial. Lacroix A, Gu F, Gallardo W, Pivonello R, Yu Y, Witek P, Boscaro M, Salvatori R, Yamada M, Tauchmanova L, Roughton M, Ravichandran S, Petersenn S, Biller BMK, Newell-Price J; Pasireotide G2304 Study Group. Lancet Diabetes Endocrinol. 2018 Jan;6(1):17-26. doi: 10.1016/S2213-8587(17)30326-1. Epub 2017 Oct 12. Erratum in: Lancet Diabetes Endocrinol. 2018 Jan;6(1):e1.

Awards:

Award 2020-21

For Student

DM (Endocrinology) Course:

There are three registrations (seats) available per year for DM Endocrinology course. This course has been recognized by Medical Council of India (MCI). The process of application/ appointment is common as mentioned under specialty registrations.

Total Passed DM Students till 2021:- 65 Students

Diploma in Diabetes:

At present one seat per year is available for Diploma in Diabetes. The process of application/ appointment is common as mentioned under specialty registrations.

Till date 47 DM Endocrinology students have passed out in these years. In October 2015 recognized DM Endocrinology seats increased from 1 to 3.

Total Passed DD Students till 2021:- 31 Students

PhD and MSc in Applied Biology:

Department is recognized by the university for PhD in Applied Biology. We enroll one student per year on availability. We also enroll MSc in Applied Biology students in our department.

Endocrine Oncology Fellowship:

Endocrine Oncology fellowship of 1 year duration Introduced in the year 2020 with an intake of

• Current Fellows:- 1. Dr. Saba Memon
  2. DrManjiriKarlekar
  3. Dr. Vikrant Gosavi

Other Information

• Molecular Endocrine Laboratory for research purpose to assess genotype phenotype correlation
• Bone Mineral Densitometry ( DXA Scan)
• Library: Number of Books pertaining to Endocrinology 476 in Central Library & 489 in Departmental Library.